Our Blog

Your introductory knowledge hub for soft capsules.

Yanitsa Miteva Yanitsa Miteva

What Are Plant-Based Softgels and How Do They Actually Work?

Plant-based softgel capsules are soft capsules whose shell is built from polysaccharide film formers (principally carrageenan and modified starch) instead of animal-derived gelatin. Because polysaccharides gel by a different mechanism than gelatin, switching is not a drop-in substitution.

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Yanitsa Miteva Yanitsa Miteva

Crosslinking in Softgel Capsules: An Intro

Drug product stability testing is not exactly glamorous work. It is slow, methodical, and expensive, and when it fails, it tends to fail late, after months of effort. For softgel capsules specifically, the stakes are higher than most anticipate. 

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Yanitsa Miteva Yanitsa Miteva

Stability Testing for Softgel Capsules

Drug product stability testing is not exactly glamorous work. It is slow, methodical, and expensive, and when it fails, it tends to fail late, after months of effort. For softgel capsules specifically, the stakes are higher than most anticipate. 

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Andres Zambrano-Bravo Andres Zambrano-Bravo

Webinar Recap: CDMOs for Softgel Capsules

Last week, we hosted a webinar on CDMOs for softgel capsules that brought together an engaged audience of pharmaceutical industry professionals from around the world. The strong turnout reflects just how critical—and how complex—the topic of outsourcing softgel manufacturing has become for pharma and biotech companies navigating today's market.

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Andres Zambrano-Bravo Andres Zambrano-Bravo

Webinar Recap: Leakers in Softgel Capsules

Last week, we hosted a technical webinar on leakers in softgel capsules that attracted hundreds of attendees from pharmaceutical companies, CDMOs, and supplement manufacturers worldwide. The strong turnout confirms that leakage remains one of the most critical quality challenges in softgel manufacturing.

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Andres Zambrano-Bravo Andres Zambrano-Bravo

Meet the Expert: Pearl Pereira- Nambiar

To continue our Meet the Expert series, we're delighted to feature Pearl Pereira Nambiar, a seasoned pharmaceutical development expert with over two decades of specialized experience in analytical development strategy and regulatory science.

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Andres Zambrano-Bravo Andres Zambrano-Bravo

Webinar Recap: Crosslinking in Softgel Capsules

A few weeks ago, we hosted a webinar on crosslinking in soft gel capsules that drew an impressive audience of over 350 registrants from across the pharmaceutical industry. This remarkable turnout demonstrates that crosslinking remains a critical challenge worthy of attention for soft gel manufacturers and formulation scientists.

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Andres Zambrano-Bravo Andres Zambrano-Bravo

Meet the Expert: Vitor Antraco

To continue our Meet the Expert series, we're delighted to feature Vitor Antraco. He is a passionate softgel formulation specialist based in Sao Paulo, Brazil, with extensive experience in pharmaceutical and nutritional supplement applications. Having developed more than 15 softgel products and served as an R&D head, Vitor brings valuable insights into the art and science of softgel technology.

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Andres Zambrano-Bravo Andres Zambrano-Bravo

Softgel capsule or liquid-filled hard capsule: Which one should you choose?

Choosing the right dosage form is a critical decision in pharmaceutical development. For liquid single-unit preparations, selecting between softgel and liquid-filled hard capsulesrequires careful evaluation. Both options present distinct manufacturing challenges, cost implications, and performance characteristics. 

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Andres Zambrano-Bravo Andres Zambrano-Bravo

3 key factors for successful shell development

This article highlights 3 key aspects of shell formulation development, from raw material selection to addressing common compatibility issues. A well-designed capsule shell is the key to unlocking the full potential of the encapsulated fill, ensuring that the product remains stable throughout its shelf life.

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Andres Zambrano-Bravo Andres Zambrano-Bravo

Meet the Expert: Dr. Samir Haddouchi

To kick off our Meet the Expert series, we’re excited to feature Dr. Samir Haddouchi, Managing Director at SOTAX Pharma Services (SPS), and a leading expert in dissolution testing of softgel capsules.

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Andres Zambrano-Bravo Andres Zambrano-Bravo

Choosing the right CDMO partnership model for softgel development

In today's pharmaceutical industry, partnerships between pharmaceutical companies and Contract Development and Manufacturing Organizations (CDMOs) are crucial for the successful development and commercialization of drugs. Choosing a CDMO itself can be a game-changer.

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